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Chemistry and Biology of Heparin and Heparan Sulfate

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Published by Elsevier Science .
Written in English

Subjects:

  • Pharmacology,
  • Science/Mathematics,
  • Chemistry - Organic,
  • Science,
  • Life Sciences - Biochemistry,
  • Science / Chemistry / Organic,
  • Chemistry - General

Book details:

Edition Notes

ContributionsHari G. Garg (Editor), Robert J. Linhardt (Editor), Charles A. Hales (Editor)
The Physical Object
FormatHardcover
Number of Pages792
ID Numbers
Open LibraryOL9267544M
ISBN 100080448593
ISBN 109780080448596

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Chemistry and Biology of Heparin and Heparan Sulfate - Kindle edition by Garg, Hari G., Linhardt, Robert J., Hales, Charles A.. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Chemistry and Biology of Heparin and Heparan Sulfate.4/5(1). The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in. * Comprehensively reviews all aspects of heparin and heparan sulfate research * Uniquely describes the chemistry, biology and clinical application of heparins and heparan sulfates in one work * Provides an invaluable source of knowledge of current developments for chemists, biochemists, medical doctors, researchers, students and practitioners.   Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the Brand: Elsevier Science.

Chemistry and biology of heparin and heparan sulfate By Hari G. Garg, Robert J. Linhardt, Charles A. Hales Overview › Preview Reviews (0) Buy Search in this book Go (0) - Write review Add to my library Get this book Elsevier - $ Barnes& - $ Borders - $ Find in a library All sellers» Sponsored Links.   Many pathogens take advantage of the dependence of the host on the interaction of hundreds of extracellular proteins with the glycosaminoglycans heparan sulfate to regulate homeostasis and use heparan sulfate as a means to adhere and gain access to cells. Moreover, mucosal epithelia such as that of the respiratory tract are protected by a layer of mucin polysaccharides, which are Author: Courtney J Mycroft-West, Dunhao Su, Stefano Elli, Scott E Guimond, Gavin J Miller, Jeremy E Turnbull. 2. Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Crown 5. School of Chemistry, Keele University, Newcastle-Under-Lyme, Staffordshire, ST5 5BG, United Kingdom. hundreds of extracellular proteins with the glycosaminoglycans heparan sulfate to regulate homeostasis and use heparan sulfate as a means Author: Courtney J Mycroft-West, Dunhao Su, Stefano Elli, Scott E Guimond, Gavin J Miller, Jeremy E Turnbull. Heparan sulfate (HS) is a member of the glycosaminoglycans (GAG) family that plays essential roles in biological processes from animal sources. Heparin, a highly sulfated form of HS, is widely used as anticoagulant drug worldwide. The high diversity and complexity of HS and heparin represent a Cited by:

Heparin vs. Heparan Sulfate. Heparin is only produced by mast cells. It functions as an anticoagulant. HS is made by almost all cell types and also has anticoagulant activity, but it is much lower than that of heparin. HS further varies from heparin in the degree of modification of the sugar residues.   The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, Brand: Elsevier Science. ISBN: OCLC Number: Description: xviii, illustrations (some color) ; 25 cm: Contents: 1. Structure and active domains of heparin / Benito Casu Structure and function of cell associated and pericellular heparan sulfate proteoglycans / Sandra G. Velleman and Caini Liu Methods for structural analysis of heparin and heparan sulfate / Ishan Capila. Ching-Ting Tsai, Medel Manuel L Zulueta, Shang-Cheng Hung. Synthetic heparin and heparan sulfate: probes in defining biological functions. Current Opinion in Chemical Biology , 40, DOI: /ted by: 8.